My 5 year old Fox Hound isnow drinking lots of water and urinating in the house! The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. Why the vets use this treatment after so many side effects being reported is disgusting. Did you go to the vets or not? Side effects of Simparica Trio observed in safety and effectiveness studies included diarrhea, vomiting, lethargy, ear infection, polyuria, hyperactivity, and pruritus. She gave her a shot to keep her from throwing up and took her x-rays and told me to come back the next day if she wasn't better. The affected dog must have been on Simparica Trio or Simparica for a minimum of 30 days prior to the report. I'll be calling them tomorrow. But few people read it or think it must be a million to one problem. At the same time, Simparica Trio is used to prevent heartworm and lungworm disease (both caused by blood worms that infect the heart and blood vessels supplying the lungs). Simparica 48. By the following day, she was showing symptoms of marked neurological impairment, similar to a human having suffered a stroke. Then I gave it to her again the 3rd month and the same thing happened. On August 17th, we had to rush him to the ER because he was not moving. If she continues I will be going to the vet. I have an appointment this Wednesday but not sure if Im going to keep it if the cough will go away eventually. He took simparica trio 3 weeks ago and I cant wait until its out of his system! They want $5k to do a spinal tap and MRI. He had it once before with no issues. Simparica Trio covers the most common dog parasites and typically costs less than buying separate products. Back to the vet and I hope they credit my money. We are currently going through this with our nine year old dachshund. Billy Boy is a 9 week old Daisy Dog. I gave my 10 year old Bull Terrier a dose of Simparico Trio Thursday December 3. GAGA-gated channels help to calm nerve transmissions, which sarolaner alters, creating an influx of nerve transmissions. This was the only thing we changed, I am convinced this is what did it to her. I give my dogs Simparica at the beginning of each month. Pyrantel Pamoate was first approved in 1977 for the treatment and . By the evening she lost the use of her hind legs. Hi i have only had my pup for about a week and a half i took him to vet and asked what would be safe to use since my pup is only about 11weeks old and weighs 4pds (prob less today) i gave him this medicine last nite and wish i would have seen this post sooner Now i pray he makes it thru the night. The FDA has approved this product for use in dogs between 5.6 and 11 pounds 1. She keeps running through the house as though looking for something. They were taking Simperica for flea/tick and Heartguard to prevent heart worms. My Irish setter is weak on her left side, left side of her face is drooping and she now carries her head with a tilt to the left. Monday, Tuesday, Wednesday and Thursday he slept all day, was hesitant to get up, wouldn't play with his ball, continued to drink excessively and shivered. This went on for 4 hours. This was days ago when I could still get food into him and the result. My vets comment was I would know if his symptoms were related if at time for next dose his symptoms were gone they are gone. Simparica Trio chewable tablets for dogs 44-88 lbs My sweet, funny, smart as can be baby girl died on 9/26/20. I bought chicken last night he ate some of that . Thank you for this information. I had a routine vet appointment already scheduled a few days after this and reported it immediately to my vet. The reaction lasted less than 12 hours. What scared me and caused me to start doing some more research is while drinking he stops and acts as if he has a lot of peanut butter in his mouth. I paid $120 for 6 months of poison. I thought it was them not liking the food and made a change. It comes in a pack of six or 12, but veterinarians typically sell individual doses for growing puppies. During this period coincidentally I have noticed a change in his behaviour. She has been treated by this clinic since birth. It seemed impossible that our boy could age years in literally 3 days. Hi, how much charcoal did you administer? It has been five days and the diarrhea started on day 2. We trusted our Vet when he recommended this over Revolution topical anti-tic/flea medication. He eats and drinks fine but looks like we havent fed him in days. But anyways - the other night , his feet collapsed from under him & he fainted . She is scared of her own shadow, walks into things at times, trips and stumbles, has become very timid, stares at the wall and has to have either me or my husband in sight at all times. She's a Brittany (Spaniel). She seems to be feeling better but still very concerned of why these levels are still up. Weighing your dog regularly will ensure that you are using the correct product size. Be warned, though the video is horrifying to watch. It didnt even occur to me it could be the drug as my doctor just gave individual pills and I didnt get to read side effects. Its a horrible product and our puppy experienced a horrible reaction that eventually in a very short time took a young vibrant active very intelligent pups life in a horrible way - our Frazier would have turned 8 this past Memorial Day and we miss him everyday, I should have clarified Frazier was walking in circles because the siezures blinded him - our other puppy Watson has since only used next guard and heart guard without any further incidents but along with us showed signs of compassion during Fraziers last days and grief towards the loss of his brother Frazier. You don't think I'm going to continue with this poison. This seemed like perfect treatment 3 in 1 but at what cost? I dont know whether its a coincidence or not, but 4 days after second dose of Simparica Trio, my dog ended up at an urgent care with blood in his urine. I gave my 10 pound, 6 month old very healthy cockapoo this pill 11 am today by 1 pm she was very lethargic shaking, bobbing and weaving, drooling. This happened the same to my dog.. how si going now with your pet? Reading all these similar cases cant figure out how the hell this crap is still being prescribed. I called the owner of my puppy's mom and she told me that the mom NEVER eats that stuff. best of luck to all whose furry ones have gotten sick from this and as well hugs to those who lost their beloved pets. Get the dog moms and dads in your life something unique this year. Just wanted to share my experience in case anyone else has similar experience with dog's character changing. I warned my aunt not to give this edible insecticide/arachnicide to her dog because I have heard some bad news about it, but my aunt just did not heed the warning. He is just laying in his crate . gave this to my dog three different times. I was furious with the drug and the prescriber too. Its now about May 16th 2021. - she's had several episodes since then. I had to put him laundry room for the night (no Carpet). Does anybody know how long this will last? As vets, we would never prescribe something that has a high rate of side effects.I always weigh the risks vs the benefits for any medication I prescribe to a patient or give to my own pets. I took him to the ER they checked his vitals and sent me home. I gave my sweet little toy poodle Simpaica today, and one hour later this poor dog went from happy and healthy to having a terrible seizure. I just wish I could find a vet who honestly loves my animals as much as I do. I will be changing clinics immediately. This leads to tick and flea death. They got him to eat a little the next morning and sent him home. Consulting vet and will not give Simparica ever again. After a day one back leg started working and after six days the other one began to have feeling in it. I am sure simparica caused a fatal seizure in my boxer. Could this be caused by the med? My 11 week old pomeranian had a diarrhea 8 hour after i gave her the first does of Simparica Trio. I just cross my fingers every day that she will get better after this is out of her system. Her protein levels dropped to almost nothing and stomach filled with fluid. He seemed okay with his next dose January 1, so we renewed the prescription, and I gave him the February dose too. He said it would take care of ticks and Trifexis doesn't. Next she developed severe tremors. The active ingredient of Simparica, sarolaner, belongs to a newer class of flea and tick preventatives called isoxazolines. Hi, I was just wondering how long you continued on with the steroids with your puppy. I am so fortunate the neurologist printed me that paper and I'm so glad that we can discontinue this medication and hopefully see him return to the quality of life he deserves! I'm so scared. His first was a week after taking his simparica. He had never pooped in the house and now he does every time he has to be put in his indoor pen for us to leave or sleep. Sunday I started watching how much water he was drinking feeling bad that I was restricting him, so I made sure to take him out to pee every few hours. I know Dukes problems were from this medicine, and it upsets me that my vet told me that this medicine was safe! For all symptoms to be reversed & to return to normal . Sorry man, that is horrible. Well, let me tell you: THANK YOU ALL FROM THE BOTTOM OF MY HEART. well my lola went into labor xmas day. Any advice on the diarrhea? I dont know. Get practical pet health tips, articles, and insights from our veterinary community delivered weekly to your inbox. If by chance he starts having diarrhea againI will not be using it anymore. What kind of supplements are you giving her? He's a 1 1/2 y.o. If my dog dies, which does not look too good right now for him, I will stop at nothing to make the company's life miserable. Now her dog is very sick and she has to take the dog to the vet every day in the past week. He had no medical problems before this, and I took him to the vet every year he ended up dying two weeks later , I took him to the vet first they told me he wasnt gonna make it to leave him there and I told him no if he isnt gonna make it, hes going to pass away in my arms at home with me and his family why took him to a different vet not the same one I confronted the woman that gave me that medicine. Our two year old dog took the same thing and thank god she has no symptoms. And a bit more stumbling. We did a cortisone pack to help him manage his "arthritis" symptoms that I totally feel were related to the simparica. I want to thank everyone who posted I could not find enough information on other sites. It is also labeled for the treatment and prevention of the Gulf Coast tick, American dog tick, black-legged tick, lone star tick, and brown dog tick. 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